Epigenetic changes associated with oocyte aging
نویسندگان
چکیده
منابع مشابه
Maintained memory in aging is associated with young epigenetic age
Epigenetic alterations during aging have been proposed to contribute to decline in physical and cognitive functions, and accelerated epigenetic aging has been associated with disease and all-cause mortality later in life. In this study, we estimated epigenetic age dynamics in groups with different memory trajectories (maintained high performance, average decline, and accelerated decline) over a...
متن کاملDendritic spine changes associated with normal aging.
Given the rapid rate of population aging and the increased incidence of cognitive decline and neurodegenerative diseases with advanced age, it is important to ascertain the determinants that result in cognitive impairment. It is also important to note that much of the aged population exhibit 'successful' cognitive aging, in which cognitive impairment is minimal. One main goal of normal aging st...
متن کاملPhysiological Changes Associated with Aging and Immobility
Aging, an inevitable and extremely complex, multifactorial process, is characterised by the progressive degeneration of organ systems and tissues. It is largely determined by genetics, and influenced by a wide range of environmental factors, such as diet, exercise, exposure to microorganisms, pollutants, and ionising radiation. This explains why two people of the same age may differ markedly in...
متن کاملChanges in thrombelastograph variables associated with aging.
Aging is associated with hypercoagulability. To assess thrombelastography (TEG) variables associated with aging, 132 adult patients of various ages undergoing orthopedic surgery for fracture repair had venous blood samples withdrawn for testing of recalcified TEG before the induction of anesthesia. Age was weakly correlated with all TEG variables: r time (R) (r = -0.45, P < 0.001; R = 19.5 - 0....
متن کاملMethylome Analysis and Epigenetic Changes Associated with Menarcheal Age
Reproductive factors have been linked to both breast cancer and DNA methylation, suggesting methylation as an important mechanism by which reproductive factors impact on disease risk. However, few studies have investigated the link between reproductive factors and DNA methylation in humans. Genome-wide methylation in peripheral blood lymphocytes of 376 healthy women from the prospective EPIC st...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Science China Life Sciences
سال: 2012
ISSN: 1674-7305,1869-1889
DOI: 10.1007/s11427-012-4354-3